Rent The Cottages - Vacation Rentals in Saint Francis Medical Center

Drury Plaza Hotel Cape Girardeau Conference Center From US $128
         

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9.4 (629 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pet Friendly
Rockwood Inn From US $181
         

10.0 (19 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • TV
Drury Inn & Suites Cape Girardeau From US $109
         

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9.4 (510 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pet Friendly
Drury Plaza Hotel Cape Girardeau Conference Center From US $113
         

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9.6 (1010 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Fairfield by Marriott Inn & Suites Cape Girardeau From US $138
         

Hampton Inn Cape Girardeau I 55 East From US $119
         

9.6 (789 Reviews)
Hotel
  • Air Conditioner
  • Parking
  • Pool
Quaint, Beautiful Home next to SEMO and Hospital From US $155
         

Little Blue Cottage on Spanish From US $101
         

8.4 (49 Reviews)
House
  • Security/Safety
  • Internet
Next Door to Mercy Hospital - Pet Friendly - Fast Wifi From US $201
         

Cozy upstairs unit in Cape Girardeau From US $140
         

New
House
  • Air Conditioner
  • Security/Safety
  • Bedding/Linens
Newly re-listed downtown historic apartment From US $134
         

10.0 (2 Reviews)
Apartment
  • Air Conditioner
  • TV
  • Balcony/Terrace
Downtown Cape Getaway with River Views From US $150
         

10.0 (1 Review)
Apartment
  • Air Conditioner
  • Parking
  • TV
Stay in the "Gone Girl" neighborhood From US $103
         

9.6 (69 Reviews)
Apartment
  • Air Conditioner
  • Parking
  • Pet Friendly
Pro Tip: Rentthecottages makes it easy to compare the best listings on Rentthecottages homes from online vacation rental OTAs, including Booking.com and more. Use the Advanced Filter feature at the top to easily flip between Rentthecottages homes, vacation rentals, bed and breakfasts, private Airbnb-style rentals availability, eco-friendly properties, property type, cancellation policies, prices, and several different options. All these make it easier to find the perfect accommodation for your next vacation in Saint Francis Medical Center.

Weather in Saint Francis Medical Center

View the weather forecast for Saint Francis Medical Center before booking your Saint Francis Medical Center Vacation Rentals to confirm your best time to go.

December - February
High 60°F       Low 26°F
March - May
High 77°F       Low 40°F
June - August
High 91°F       Low 64°F
September - November
High 84°F       Low 38°F

Saint Francis Medical Center Vacation Rental Frequently Asked Questions

What are the top vacation rentals in Saint Francis Medical Center?
How many vacation rentals are available in Saint Francis Medical Center?

Currently, the total number of properties listed in 2026 is over 66 in the Saint Francis Medical Center area, and still counting. By aggregating listings from multiple websites, offers an immense amount of choice of the best properties in Saint Francis Medical Center.